A NEW DRUG FOR CHRONIC KIDNEY DISEASE

In summary, the successful demonstration of lubiprostone’s renoprotective effects via modulation of gut microbiota and mitochondrial enhancement represents a milestone in CKD research. By leveraging the drug’s dual effects on polyamine production and inflammation suppression, this approach stands to redefine treatment paradigms and inspire future investigations into microbiota-centric therapies. As Phase III trials loom on the horizon, the nephrology community eagerly anticipates further validation and potential integration of this strategy into clinical practice, ushering in a new era of kidney disease management.

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